Fig. 5
From: Alzheimer’s disease diagnosis based on the Hippocampal Unified Multi-Atlas Network (HUMAN) algorithm

Hippocampal volume variation over time. The linear model describing how hippocampal volumes from healthy subjects vary over time. HUMAN volumes of AD patients are also represented to qualitatively show the informative content of the measurements. In fact, AD subjects show a consistent reduction of the hippocampal volume compared to CTRL expected volumes