Table 1 Patient Characteristics in the Training, Internal Test, and External Test Sets
Variables | Training set (n = 216) | P | Internal test set (n = 70) | P | External test set (n = 106) | P | |||
|---|---|---|---|---|---|---|---|---|---|
Resistant (n = 64) | Sensitive (n = 152) | Resistant (n = 18) | Sensitive (n = 52) | Resistant (n = 39) | Sensitive (n = 67) | ||||
BMI, mean (SD) | 24.12 (2.62) | 23.77 (2.82) | 0.494 | 24.11 (3.08) | 24.16 (4.21) | 0.962 | 24.07 (1.84) | 23.67 (2.72) | 0.716 |
Age, mean (SD), year | 56.05 (7.92) | 56.44 (8.32) | 0.650 | 56.39 (7.39) | 57.88 (7.19) | 0.453 | 57.29 (8.13) | 57.54 (8.29) | 0.823 |
CA125, mean (SD), ng/ml | 1592.48 (1351.93) | 1440.51 (1243.02) | 0.486 | 1327.58 (1437.53) | 1223.59 (1113.01) | 0.753 | 1337.68 (1303.16) | 1204.37 (1058.11) | 0.689 |
PFI, mean (SD), month | 4.52 (1.79) | 18.95 (13.02) | <.001 | 4.39 (1.88) | 21.52 (16.87) | <.001 | 4.74 (1.72) | 22.35 (14.36) | <.001 |
Type of surgery, No. (%) | 0.748 | 0.935 | 0.951 | ||||||
PDS | 21 (32.81) | 46 (30.26) | 3 (16.67) | 7 (13.46) | 7 (17.95) | 13 (19.40) | |||
IDS | 43 (67.19) | 106 (69.74) | 15 (83.33) | 45 (86.54) | 32 (82.05) | 54 (80.60) | |||
HIPEC, No. (%) | 0.695 | 0.211 | 0.842 | ||||||
No | 29 (45.31) | 68 (44.74) | 14 (77.78) | 32 (61.54) | 23 (58.97) | 38 (56.72) | |||
Yes | 35 (54.69) | 84 (55.26) | 4 (22.22) | 20 (38.46) | 16 (41.03) | 29 (43.28) | |||
Histologic classification, n (%) | 0.349 | 0.624 | 0.481 | ||||||
High grade serous carcinoma | 59 (92.19) | 121 (79.61) | 16 (88.89) | 45 (86.54) | 34 (87.18) | 57 (85.07) | |||
Endometrioid carcinoma | 0 (0.00) | 6 (3.95) | 0 (0.00) | 1 (1.92) | 0 (0.00) | 2 (2.99) | |||
Clear cell carcinoma | 1 (1.56) | 3 (1.97) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (1.49) | |||
Mucinous carcinoma | 0 (0.00) | 2 (1.32) | 0 (0.00) | 1 (1.92) | 1 (2.56) | 0 (0.00) | |||
Low grade serous carcinoma | 4 (6.25) | 20 (13.15) | 2 (11.11) | 5 (9.62) | 4 (10.26) | 7 (10.45) | |||
FIGO stage, n (%) | 0.858 | 0.820 | 0.871 | ||||||
II | 4 (6.25) | 6 (3.95) | 1 (5.56) | 2 (3.85) | 1 (2.56) | 2 (2.99) | |||
III | 54 (84.38) | 127 (83.55) | 15 (83.33) | 47 (90.38) | 33 (84.62) | 54 (80.60) | |||
IV | 6 (9.37) | 19 (12.50) | 2 (11.11) | 3 (5.77) | 5 (12.82) | 11 (16.42) | |||